Exploring the Therapeutic Potential of Canarium resiniferum Leaves: Anxiolytic, Antidepressant, and Antioxidant Properties of Methanol Extracts

Abstract:

Medicinal plants have served as a cornerstone of traditional medicine, providing a vast array of bioactive compounds for therapeutic development. Among these, Canarium resiniferum, a lesser-known species of the Burseraceae family, has recently gained attention for its diverse pharmacological properties. This review focuses on the anxiolytic, antidepressant, and antioxidant activities of methanol extracts from Canariumresiniferum leaves. The phytochemical constituents underlying these bioactivities, including flavonoids, phenolics, and alkaloids, are explored in detail. Experimental findings demonstrate the plant’s significant potential in modulating key central nervous system pathways and combating oxidative stress. Challenges such as standardization, isolation of active compounds, and clinical validation are discussed alongside future research directions. This review highlights Canarium resiniferum as a promising source of natural therapeutics for addressing mental health disorders and oxidative stress-related conditions.