Original Research Article – Traditional medicine

April 19, 2026

Comprehensive Phytochemical Characterization and Molecular Insights into the Anticancer Activity of Itrifal-e-Aftimoon: An Integrated HPLC-DAD, LC-MS/MS, and Mechanistic Approach

Introduction Cancer continues to represent one of the foremost global health burdens, with conventional chemotherapy, radiotherapy and targeted agents constrained by toxicity, acquired resistance and limited accessibility in resource-poor settings [1]. Approximately 60% of currently used anticancer drugs are derived from natural products or their synthetic analogues [2], and this has renewed scientific interest in traditional pharmacopoeias including Ayurveda, Traditional…

Original Research Article 0 11 min read

April 14, 2026

Apigenin ‘s Dual Action on Pain and Inflammation: Mechanistic Insights Through NO, COX, and Oxidative Stress Pathways

Flavonoids constitute a broad class of naturally occurring polyphenolic compounds that are widely distributed in fruits, vegetables, herbs, and medicinal plants. These bioactive compounds are well recognized for their diverse pharmacological properties, including antioxidant, anti-inflammatory, analgesic, antimicrobial, and neuroprotective activities [1]. Due to their significant therapeutic potential and relatively low toxicity, flavonoids have attracted considerable scientific attention as promising candidates…

Original Research Article 0 18 min read

January 7, 2026

Import substitution within the framework of global trade in Medicinal Plants: A potential consideration for homologated phytomedicines in Cameroon

INTRODUCTION Import substitution is a well-intended economic concept geared towards meeting the needs of a wider sector of a nation’s general demand for goods (production and imports), by her self-domestic production [1, 2]. Import substitution within the framework of the medicinal plants sector has generated more interest in Cameroon as the country reflects on her vision 2035 economic plan. Efforts…

Original Research Article 0 37 min read

December 8, 2025

Ferumoxytol: A Multifunctional Nanomedicine for Iron Deficiency synthesised

Introduction Ferumoxytol is a colloidal superparamagnetic iron-carbohydrate complex that has been widely used as an intravenous iron replacement therapy for patients suffering from iron deficiency anaemia (IDA) and those with chronic kidney disease (CKD).[1] Traditional iron supplements, including oral formulations, often present challenges such as poor bioavailability, gastrointestinal intolerance, and a prolonged treatment timeline. Intravenous iron therapies, including Ferumoxytol, provide…

Original Research Article 0 20 min read

November 20, 2025

A comprehensive review of enhanced bioavailability, nutraceutical efficacy, and superior manufacturing quality of Liposomal Curcumin by WBCIL

1. Introduction Curcumin, the principal bioactive component of Curcuma longa (turmeric), has garnered significant scientific interest due to its potent anti-inflammatory, antioxidant, and anticancer properties.[1] Despite its promising therapeutic potential, clinical application of curcumin has been severely limited by its poor water solubility, instability in physiological conditions, and rapid systemic elimination, resulting in extremely low oral bioavailability.[1] Conventional curcumin formulations…

Original Research Article 0 21 min read

November 6, 2025

First Evidence of Phyto-Melatonin as a Protective Bio-Molecule in Capra hircus

Introduction Melatonin is an evolutionarily conserved molecule found across diverse life forms [1]. Initially known for its presence in animals, it was later identified in plants during the nineteenth century, leading to the concept of phyto-melatonin—the plant-derived form of melatonin [2]. Recent research indicates that phyto-melatonin is not limited to higher plants; it is also present in various macro- and…

Original Research Article 0 24 min read

August 10, 2025

Reptile Gel as a Non-Invasive Topical Therapy for Erectile Dysfunction: Findings from the First Clinical Trial and Future Directions of WBCIL

1. Introduction Reptile Gel is an innovative topical solution for erectile dysfunction (ED), designed to offer a fast-acting, non-invasive, and drug-free alternative to traditional treatments.[1] Unlike oral medications, which require systemic absorption and may cause side effects, Reptile Gel works through a physical evaporative cooling mechanism that stimulates nerve endings in the glans penis, triggering vasodilation and increased blood flow.[2]…

Original Research Article 0 28 min read

August 5, 2025

Measuring the Risk: Hypoglycemia in Newborns of Diabetic Mothers-Cross Sectional Study

Introduction: Neonatal hypoglycemia remains one of the most frequently encountered and clinically significant metabolic issues in newborns, particularly in those with identifiable risk factors. It results from the neonate’s immature ability to regulate blood glucose after separation from the maternal circulation. Since glucose is the brain’s primary energy source and neonatal brain metabolism is exceptionally high, inadequate glucose levels can…

Original Research Article 0 23 min read

June 20, 2025

Clinical Evaluation of Reptile Gel manufactured by WBCIL: Vasodilation, Temperature Modulation, and Improved Penile Blood Flow

Introduction Erectile dysfunction (ED) is a prevalent male sexual health disorder, affecting an estimated 150–200 million men worldwide, with incidence rising sharply with age and comorbid conditions such as diabetes, hypertension, and cardiovascular disease.[1] The condition has a profound impact on quality of life, self-esteem, and intimate relationships, making effective management a critical clinical and social need.[2] Current therapeutic options…

Original Research Article 0 19 min read

June 17, 2025

Efficacy of Qurs-e-Habis in the Management of Menorrhagia: A Multi-centric Clinical Study

Introduction Menorrhagia, known as Kasrat-e-Tams in Unani medicine, represents one of the most prevalent gynecological disorders affecting women of reproductive age globally. Heavy menstrual bleeding (HMB) is clinically defined as excessive menstrual blood loss that significantly interferes with a woman’s physical, social, emotional, and material quality of life, either occurring independently or in combination with other symptoms [1-2]. The condition…