Measuring the Risk: Hypoglycemia in Newborns of Diabetic Mothers-Cross Sectional Study

Abstract:

Neonatal hypoglycemia is a prevalent metabolic disorder in newborns, often resulting from impaired glucose regulation. As glucose is a critical energy source for the developing brain, its deficiency can significantly affect neurological and physical development. Despite extensive  research globally, there is a lack of recent data from our region. This study aims to determine the frequency of hypoglycemia among neonates born to diabetic mothers in our local population. The findings are intended to support improved clinical management, guide future recommendations, and contribute to ongoing research efforts.

Objective: To determine the frequency of hypoglycemia in newborn of diabetic  mother

Study Settings: Neonatal ICU Pediatric Department, Saidu  Group of Teaching Hospitals Saidu Sharif Swat.

Study Design: Cross-sectional study.

Duration of Study: Six months from 15/12/2020 to  15/6/2021

Materials and methods: This study included 231 diabetic mothers. Medical histories and diagnostic tests confirmed maternal diabetes. A 3 ml blood sample from each newborn was analyzed by experienced pathologists. Hypoglycemia was defined as a serum glucose level below 46 mg/dL.

Results: Among 231 mothers, 81 (35%) were aged 18–30 years and 150 (65%) were aged 31–40 years. Of the 231 newborns, 134 (58%) were male and 97 (42%) were female. Hypoglycemia was observed in 42 neonates (18%), while 189 (82%) had normal glucose levels.

Conclusion: The frequency of hypoglycemia in neonates of diabetic mothers was found to be 18%. These findings highlight the need for early screening and appropriate management in this high-risk group.