Ferumoxytol: A Multifunctional Nanomedicine for Iron Deficiency synthesised

Abstract:

Ferumoxytol, a colloidal superparamagnetic iron-carbohydrate complex, has emerged as a highly effective intravenous iron replacement therapy, particularly for patients with iron deficiency anaemia (IDA) and IDA associated with chronic kidney disease (CKD). Unlike traditional iron supplements, Ferumoxytol offers rapid and efficient iron replenishment with minimal side effects, addressing key challenges such as poor bioavailability and gastrointestinal intolerance. Its unique nanoparticle formulation, consisting of iron oxide cores coated with a biocompatible dextran shell, enhances stability and reduces immunological reactivity. Additionally, its potential in targeted molecule delivery underscores its growing relevance in nanomedicine. The synthesis process, employed by West Bengal Chemical Industries Ltd. (WBCIL), ensures the production of high-purity, biocompatible nanoparticles with optimized therapeutic performance. This study explores nutraceutical applications of Ferumoxytol and its advanced synthesis process conducted by WBCIL.